Drug General Information
Drug ID	D01OFY
Former ID	DIB008040
Drug Name	LAS-31180
Drug Type	Small molecular drug
Indication	Heart failure [ICD9: 428; ICD10:I50]		Terminated	[525948]
Company	Almirall Prodesfarma SA
Structure		Download 2D MOL 3D MOL
Formula	C11H12N2O3S
Canonical SMILES	CN1C=C(C(=O)C2=CC=CC=C21)NS(=O)(=O)C
InChI	1S/C11H12N2O3S/c1-13-7-9(12-17(2,15)16)11(14)8-5-3-4-6-10(8)13/h3-7,12H,1-2H3
InChIKey	LSIYNVMXGMDGMG-UHFFFAOYSA-N
PubChem Compound ID	195841
PubChem Substance ID	10262120, 15416533, 33516123, 50815678, 57398376, 103831363, 113461651, 117631837, 125718071, 128534743, 135173899, 232921059
Target and Pathway
Target(s)	CGMP-inhibited 3',5'-cyclic phosphodiesterase A	Target Info	Modulator	[525948]
KEGG Pathway	Purine metabolism
	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Morphine addiction
Reactome	cGMP effects
	G alpha (s) signalling events
WikiPathways	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 525948	Pharmacological profile of LAS 31180, a new inotropic/vasodilator quinolone derivative. Arzneimittelforschung. 2000 Nov;50(11):980-6.
Ref 525948	Pharmacological profile of LAS 31180, a new inotropic/vasodilator quinolone derivative. Arzneimittelforschung. 2000 Nov;50(11):980-6.

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