Drug Information

Drug General Information
Drug ID
D01OUA
Former ID
DIB005013
Drug Name
TJN-598
Synonyms
Glomerulonephritis therapy, Tsumura
Indication Glomerulonephritis [ICD9: 580-582; ICD10:N00, N01, N03, N18] Terminated [531152]
Company
Tsumura & Co
Target and Pathway
Target(s) CAMP-specific 3',5'-cyclic phosphodiesterase 4B Target Info Inhibitor [531152]
Type IV phosphodiesterase Target Info Inhibitor [531152]
CAMP-specific 3',5'-cyclic phosphodiesterase 4A Target Info Inhibitor [531152]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addictionhsa00230:Purine metabolism
Morphine addiction
NetPath Pathway IL5 Signaling Pathway
IL2 Signaling Pathway
PathWhiz Pathway Purine Metabolism
Reactome DARPP-32 events
G alpha (s) signalling eventsR-HSA-180024:DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
Myometrial Relaxation and Contraction Pathways
Nuclear Receptors Meta-Pathway
Opioid SignallingWP35:G Protein Signaling Pathways
TSH signaling pathwayWP35:G Protein Signaling Pathways
References
Ref 531152Effects of TJN-598, a new selective phosphodiesterase type IV inhibitor on anti-Thy1 nephritis in rats. Clin Exp Nephrol. 2011 Feb;15(1):14-24.
Ref 531152Effects of TJN-598, a new selective phosphodiesterase type IV inhibitor on anti-Thy1 nephritis in rats. Clin Exp Nephrol. 2011 Feb;15(1):14-24.

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