Drug Information

Drug General Information
Drug ID
D01RSH
Former ID
DNC007310
Drug Name
2-(3-bromobenzoylamino)-4-chlorobenzoic acid
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527354]
Structure
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2D MOL

3D MOL
Formula
C14H9BrClNO3
Canonical SMILES
C1=CC(=CC(=C1)Br)C(=O)NC2=C(C=CC(=C2)Cl)C(=O)O
InChI
1S/C14H9BrClNO3/c15-9-3-1-2-8(6-9)13(18)17-12-7-10(16)4-5-11(12)14(19)20/h1-7H,(H,17,18)(H,19,20)
InChIKey
NKUSVNRZDILGSG-UHFFFAOYSA-N
PubChem Compound ID
4323128
Target and Pathway
Target(s) Glutamate receptor, ionotropic kainate 1 Target Info Inhibitor [527354]
KEGG Pathway Neuroactive ligand-receptor interaction
Glutamatergic synapse
PANTHER Pathway Huntington disease
Ionotropic glutamate receptor pathway
Metabotropic glutamate receptor group III pathway
Metabotropic glutamate receptor group I pathway
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 527354J Med Chem. 2004 Dec 30;47(27):6948-57.Bioisosteric modifications of 2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.
Ref 527354J Med Chem. 2004 Dec 30;47(27):6948-57.Bioisosteric modifications of 2-arylureidobenzoic acids: selective noncompetitive antagonists for the homomeric kainate receptor subtype GluR5.

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