Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D01UGG
|
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| Former ID |
DIB004547
|
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| Drug Name |
Sabarubicin
|
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| Synonyms |
BMS-195615; MEN-10755
|
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| Drug Type |
Small molecular drug
|
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| Indication | Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] | Phase 2 | [1] | ||
| Company |
The Menarini Group
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C32H37NO13
|
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| Canonical SMILES |
c12c(C(=O)c3c(C1=O)cccc3)c(c1c(c2O)C[C@](C[C@@H]1O[C@@H<br />]1O[C@H]([C@H]([C@H](C1)O)O[C@@H]1O[C@H]([C@H]([C@H](C1<br />)N)O)C)C)(C(=O)CO)O)O
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | DNA topoisomerase II | Target Info | Modulator | [2] | |
| References | |||||
| REF 1 | ClinicalTrials.gov (NCT00027781) MEN-10755 in Treating Patients With Progressive Prostate Cancer That Has Not Responded to Hormone Therapy. U.S. National Institutes of Health. | ||||
| REF 2 | Interpreting expression profiles of cancers by genome-wide survey of breadth of expression in normal tissues. Genomics 2005 Aug;86(2):127-41. | ||||
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