Drug General Information
Drug ID
D01WBD
Former ID
DIB010056
Drug Name
Mibampator
Synonyms
LY-450108; LY-451395; AMPA agonists (Alzheimer's Disease), Lilly; AMPA receptor agonist (agitation in Alzheimer's Disease), Eli Lilly
Drug Type
Small molecular drug
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Phase 2 [522580]
Company
Eli Lilly & Co
Structure
Download
2D MOL

3D MOL

Formula
C21H30N2O4S2
Canonical SMILES
c1(c2ccc(cc2)CCNS(=O)(=O)C)ccc(cc1)[C@H](CNS(=O)(=O)C(C<br />)C)C
PubChem Compound ID
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Agonist [544383]
References
Ref 522580ClinicalTrials.gov (NCT00843518) Treatment for Aggression and Agitation in Patients With Alzheimer's Disease. U.S. National Institutes of Health.
Ref 544383Mibampator (LY451395) Randomized Clinical Trial for Agitation/Aggression in Alzheimer's disease. Int Psychogeriatr. 2013 May; 25(5): 707-719.

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