TTD | Drug: D01WVV

Drug General Information
Drug ID	D01WVV
Former ID	DIB018203
Drug Name	[35S]ibutamoren
Synonyms	[35S]MK-0677
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538673]
Structure		Download 2D MOL
Formula	C27H36N4O5S
InChI	InChI=1S/C27H36N4O5S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27/h4-12,22H,13-19,28H2,1-3H3,(H,29,33)/t22-/m1/s1/i37+3
InChIKey	UMUPQWIGCOZEOY-KRTHATKOSA-N
PubChem Compound ID	10578170
PubChem Substance ID	15606318, 22885992, 41213354, 80929565, 135651124
Target and Pathway
Target(s)	Growth hormone secretagogue receptor type 1	Target Info	Agonist	[534355]
KEGG Pathway	cAMP signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
NetPath Pathway	Leptin Signaling Pathway
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538673	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1097).
Ref 534355	Molecular analysis of rat pituitary and hypothalamic growth hormone secretagogue receptors. Mol Endocrinol. 1997 Apr;11(4):415-23.

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Drug Information