Drug General Information
Drug ID	D01XGX
Former ID	DIB003724
Drug Name	JTP-4819
Synonyms	JTP-3399
Drug Type	Small molecular drug
Indication	Cognitive disorders [ICD9: 290-294, 294.0, 780.09, 780.9, 780.93; ICD10:F01-F07, F04, F05, R41.3]		Discontinued in Phase 2	[546065]
Company	Japan Tobacco Inc
Structure		Download 2D MOL 3D MOL
Formula	C19H25N3O4
Canonical SMILES	N1(C(=O)[C@H]2N(C(=O)NCc3ccccc3)CCC2)[C@H](C(=O)CO)CCC1
CAS Number	CAS 162203-65-8
PubChem Compound ID	178060
Target and Pathway
Target(s)	Prolyl endopeptidase	Target Info	Modulator	[534339]
KEGG Pathway	Renin-angiotensin system
PANTHER Pathway	Vasopressin synthesis
References
Ref 546065	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800006163)
Ref 534339	A novel prolyl endopeptidase inhibitor, JTP-4819, with potential for treating Alzheimer's disease. Behav Brain Res. 1997 Feb;83(1-2):147-51.

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