Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02AVZ
|
||||
| Former ID |
DNC002718
|
||||
| Drug Name |
2-Phenylheme
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Discovery agent | Investigative | [551393] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C36H30FeN4O2
|
||||
| Canonical SMILES |
CC1=C(C2=CC3=NC(=CC4=C(C(=C([N-]4)C(=C5C=CC(=N5)C=C1[N-<br />]2)C6=CC=CC=C6)CCC(=O)O)C)C(=C3C)C=C)C=C.[Fe+2]
|
||||
| InChI |
1S/C36H31N4O2.Fe/c1-6-25-20(3)29-17-24-13-15-28(37-24)35(23-11-9-8-10-12-23)36-27(14-16-34(41)42)22(5)31(40-36)19-33-26(7-2)21(4)30(39-33)18-32(25)38-29;/h6-13,15,17-19H,1-2,14,16H2,3-5H3,(H2-,37,38,39,40,41,42);/q-1;+2/p-1
|
||||
| InChIKey |
OKXXLWPLHDCBIL-UHFFFAOYSA-M
|
||||
| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Heme oxygenase | Target Info | Inhibitor | [551393] | |
| BioCyc Pathway | Heme degradation | ||||
| Pathway Interaction Database | Validated transcriptional targets of AP1 family members Fra1 and Fra2 | ||||
| HIF-1-alpha transcription factor network | |||||
| PathWhiz Pathway | Porphyrin Metabolism | ||||
| Reactome | Iron uptake and transport | ||||
| WikiPathways | Oxidative Stress | ||||
| Transcriptional activation by NRF2 | |||||
| NRF2 pathway | |||||
| Nuclear Receptors Meta-Pathway | |||||
| miR-targeted genes in squamous cell - TarBase | |||||
| miR-targeted genes in muscle cell - TarBase | |||||
| miR-targeted genes in lymphocytes - TarBase | |||||
| miR-targeted genes in leukocytes - TarBase | |||||
| miR-targeted genes in epithelium - TarBase | |||||
| References | |||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.