Drug General Information
Drug ID	D02BPT
Former ID	DIB018359
Drug Name	[3H]nicotine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540595]
Structure		Download 2D MOL 3D MOL
Formula	C10H14N2
InChI	InChI=1S/C10H14N2/c1-12-7-3-5-10(12)9-4-2-6-11-8-9/h2,4,6,8,10H,3,5,7H2,1H3
InChIKey	SNICXCGAKADSCV-UHFFFAOYSA-N
PubChem Compound ID	942
Target and Pathway
Target(s)	Neuronal acetylcholine receptor protein, beta-2 chain	Target Info	Agonist	[543842]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Cholinergic synapse
	Nicotine addiction
PANTHER Pathway	Nicotinic acetylcholine receptor signaling pathway
	Nicotine pharmacodynamics pathway
Reactome	Highly sodium permeable acetylcholine nicotinic receptors
	Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
	Highly calcium permeable nicotinic acetylcholine receptors
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Nicotine Activity on Dopaminergic Neurons
References
Ref 540595	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3978).
Ref 543842	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 465).

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