Drug Information

Drug General Information
Drug ID
D02DMW
Former ID
DIB005589
Drug Name
S-1360
Synonyms
GW-810781; 810781
Drug Type
Small molecular drug
Indication Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26] Phase 2 [521535]
Company
Shionogi & Co Ltd
Structure
Download
2D MOL

3D MOL
Formula
C16H12FN3O3
Canonical SMILES
c1(nc[nH]n1)/C(=C/C(=O)c1oc(cc1)Cc1ccc(F)cc1)/O
CAS Number
CAS 280571-30-4
PubChem Compound ID
6451047
Target and Pathway
Target(s) HIV integrase Target Info Inhibitor [528782], [528810]
References
Ref 521535ClinicalTrials.gov (NCT00046332) A Study Comparing 4 Doses Of GW810781 Versus Placebo In HIV-Infected Patients. U.S. National Institutes of Health.
Ref 528782Calculation of binding energy using BLYP/MM for the HIV-1 integrase complexed with the S-1360 and two analogues. Bioorg Med Chem. 2007 Jun 1;15(11):3818-24. Epub 2007 Mar 13.
Ref 528810HIV-1 integrase inhibitors: an emerging clinical reality. Drugs R D. 2007;8(3):155-68.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.