Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02GEC
|
||||
| Former ID |
DAP000387
|
||||
| Drug Name |
Omalizumab
|
||||
| Synonyms |
Xolair; Omalizumab (genetical recombination); Xolair (TN); Omalizumab (USAN/INN); Omalizumab (genetical recombination) (JAN)
|
||||
| Drug Type |
Monoclonal antibody
|
||||
| Therapeutic Class |
Antiasthmatic Agents
|
||||
| Company |
National University Hospital, Singapore|National University, Singapore
|
||||
| Formula |
C6450H9916N1714O2023S38
|
||||
| CAS Number |
CAS 242138-07-4
|
||||
| PubChem Substance ID | |||||
| SuperDrug ATC ID |
R03DX05
|
||||
| Target and Pathway | |||||
| Target(s) | High affinity immunoglobulin epsilon receptor | Target Info | Modulator | [889443] | |
| PathWhiz Pathway | Fc Epsilon Receptor I Signaling in Mast Cells | ||||
| References | |||||
| Ref 536361 | Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20. | ||||
| Ref 541948 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6890). | ||||
| Ref 889349 | ClinicalTrials.gov (NCT00546143) Safety and Tolerability of Omalizumab in Patients With Mild to Moderate Asthma | ||||
| Ref 889383 | ClinicalTrials.gov (NCT01701583) Effect of Omalizumab (Xolair) on Basophils in Patients With Chronic Idiopathic Urticaria | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.