Drug Information

Drug General Information
Drug ID
D02HDI
Former ID
DIB018872
Drug Name
arachidonylcyclopropylamide
Synonyms
arachidonyl cyclopropylamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542410]
Structure
Download
2D MOL
Formula
C23H37NO
InChI
InChI=1S/C23H37NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(25)24-22-20-21-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3,(H,24,25)/b7-6-,10-9-,13-12-,16-15-
InChIKey
GLGAUBPACOBAMV-DOFZRALJSA-N
PubChem Compound ID
5311007
PubChem Substance ID
7978724, 11056205, 14875871, 26755749, 39340740, 49964828, 52369795, 58762623, 91702879, 103178967, 114155037, 134224292, 135651444, 137249613, 140908979, 162254922, 164835929, 232233635, 241182324, 241375358, 242056982, 252156088, 252457735, 252466604
Target and Pathway
Target(s) Cannabinoid receptor 1 Target Info Agonist [525498]
GPR18 Target Info Agonist [531489]
KEGG Pathway Rap1 signaling pathway
Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
PANTHER Pathway Endogenous cannabinoid signaling
Pathway Interaction Database N-cadherin signaling events
Reactome Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Small Ligand GPCRs
BDNF signaling pathway
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 542410(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 739).
Ref 525498Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J Pharmacol Exp Ther. 1999 Jun;289(3):1427-33.
Ref 531489Delta(9) -Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells. Br J Pharmacol. 2012 Apr;165(8):2414-24.

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