TTD | Drug: D02KAF

Drug General Information
Drug ID	D02KAF
Former ID	DIB011815
Drug Name	GT-2203
Synonyms	GT-2144; GT-2203; GT-2204; GT-2223; GT-2328; GT-2396; GT-2397; GT-2431; H3 agonists, Gliatech
Indication	Anxiety disorder [ICD9: 300, 311; ICD10:F32, F40-F42]		Terminated	[546559]
Company	Gliatech Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	[C@H]1(C[C@H]1N)c1nc[nH]c1
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Agonist	[543673]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 546559	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008938)
Ref 543673	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264).

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Drug Information