Drug Information

Drug General Information
Drug ID
D02KIM
Former ID
DIB019462
Drug Name
compound 36j
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531459], [541089]
Structure
Download
2D MOL
Formula
C22H24ClN5O3S
InChI
InChI=1S/C22H24ClN5O3S/c1-13-21(27-20-7-2-14(11-24)8-19(20)23)25-12-26-22(13)31-17-9-15-3-4-16(10-17)28(15)32(29,30)18-5-6-18/h2,7-8,12,15-18H,3-6,9-10H2,1H3,(H,25,26,27)/t15-,16-/m0/s1
InChIKey
JONDVPWMQDOELC-HOTGVXAUSA-N
PubChem Compound ID
54587590
PubChem Substance ID
131347447, 178102380, 237405168
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [531459]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 531459Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3290-6.
Ref 541089(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5755).
Ref 531459Discovery of a nortropanol derivative as a potent and orally active GPR119 agonist for type 2 diabetes. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3290-6.

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