Drug Information

Drug General Information
Drug ID
D02LVZ
Former ID
DAP000800
Drug Name
Darbepoetin alfa
Synonyms
Aranesp (TN)
Indication Anemia [ICD9: 280-285; ICD10:D50-D64] Approved [537115]
Therapeutic Class
Antianemic Agents
Company
Amgen Inc
Formula
C815H1317N233O241S5
CAS Number
CAS 11096-26-7
SuperDrug ATC ID
B03XA02
Target and Pathway
Target(s) Erythropoietin Receptor Target Info Agonist [534882]
KEGG Pathway Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database Signaling events mediated by Stem cell factor receptor (c-Kit)
EPO signaling pathway
WikiPathways EPO Receptor Signaling
References
Ref 537115Emerging treatments for traumatic brain injury. Expert Opin Emerg Drugs. 2009 Mar;14(1):67-84.
Ref 534882A cytosolic domain of the erythropoietin receptor contributes to endoplasmic reticulum-associated degradation. Eur J Biochem. 1999 Jul;263(2):410-9.

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