TTD | Drug: D02NMG

Drug General Information
Drug ID	D02NMG
Former ID	DPR000107
Drug Name	SLV-332
Drug Type	Small molecular drug
Indication	Irritable bowel syndrome [ICD9: 564.1, 787.91; ICD10:A09, K58, K59.1]		Preclinical	[536224]
Company	Solvay
Structure		Download 2D MOL 3D MOL
Formula	C30H39N3O5S
Canonical SMILES	CC(C)CCOC1=CC=C(C=C1)NC(=S)NC2=CC=C(C=C2)OCCC(C)C.C1=CC<br />(=C(C=C1N)O)C(=O)O
InChI	1S/C23H32N2O2S.C7H7NO3/c1-17(2)13-15-26-21-9-5-19(6-10-21)24-23(28)25-20-7-11-22(12-8-20)27-16-14-18(3)4;8-4-1-2-5(7(10)11)6(9)3-4/h5-12,17-18H,13-16H2,1-4H3,(H2,24,25,28);1-3,9H,8H2,(H,10,11)
InChIKey	HHBOLVQEBVCBNA-UHFFFAOYSA-N
CAS Number	CAS 910-86-1
PubChem Compound ID	3002337
PubChem Substance ID	637391, 34667915, 79275308, 111611645, 134339205, 134339546
SuperDrug ATC ID	J04AD02
SuperDrug CAS ID	cas=000910861
Target and Pathway
Target(s)	NK-2 receptor	Target Info	Antagonist	[536224]
KEGG Pathway	Calcium signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	G alpha (q) signalling events
WikiPathways	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 536224	Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.
Ref 536224	Emerging drugs for irritable bowel syndrome. Expert Opin Emerg Drugs. 2006 May;11(2):293-313.

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Drug Information