Drug Information

Drug General Information
Drug ID
D02TJT
Former ID
DNCL003833
Drug Name
MK-8109
Indication Platinum-resistant ovarian cancer [ICD9: 140-229, 183; ICD10:C56] Phase 3 [549855]
Company
Merck
Target and Pathway
Target(s) Folate receptor alpha Target Info Modulator [544488]
KEGG Pathway Endocytosis
Reactome COPII (Coat Protein 2) Mediated Vesicle Transport
Cargo concentration in the ER
WikiPathways Folate Metabolism
References
Ref 549855Clinical pipeline report, company report or official report of Endocyte.
Ref 544488A current review of folate receptor alpha as a potential tumor target in non-small-cell lung cancer. Drug Des Devel Ther. 2015; 9: 4989-4996.

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