Drug Information

Drug General Information
Drug ID
D02VBF
Former ID
DIB018012
Drug Name
BI-D1870
Drug Type
Small molecular drug
Indication Chronic lymphocytic leukaemia [ICD10:C91] Preclinical [528477]
Structure
Download
2D MOL
Formula
C19H23F2N5O2
InChI
InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24)
InChIKey
DTEKTGDVSARYDS-UHFFFAOYSA-N
PubChem Compound ID
25023738
PubChem Substance ID
56374161, 57539505, 58088277, 81043444, 103694291, 118847198, 123124574, 125362031, 126531503, 131408220, 135685188, 135685189, 135685208, 136368051, 144115704, 152058298, 152344438, 162009825, 162012025, 162201842, 163163891, 163620707, 163685623, 163686024, 170495491, 180371698, 184824669, 210024009, 223398086, 223671510, 238870382, 241103234, 242060180, 249565718, 252160224, 252214989, 252437834, 252543290
Target and Pathway
Target(s) ribosomal protein S6 kinase, 90kDa, polypeptide 2 Target Info Inhibitor [528477]
ribosomal protein S6 kinase, 90kDa, polypeptide 1 Target Info Inhibitor [528477]
ribosomal protein S6 kinase, 90kDa, polypeptide 3 Target Info Inhibitor [528477]
ribosomal protein S6 kinase, 90kDa, polypeptide 6 Target Info Inhibitor [528477]
References
Ref 528477BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. Biochem J. 2007 Jan 1;401(1):29-38.
Ref 528477BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoforms in vitro and in vivo. Biochem J. 2007 Jan 1;401(1):29-38.

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