Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02WQR
|
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| Former ID |
DIB012808
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| Drug Name |
GSK-008A
|
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| Synonyms |
GSK-008A; Progesterone receptor agonists (gynecological disorder); Progesterone receptor agonists (gynecological disorder), GSK
|
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| Indication | Gynecological disorder [ICD10:N70-N98] | Investigative | [1] | ||
| Company |
GlaxoSmithKline plc
|
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
c1n(c(nn1)C(N(c1ccc(c(c1)Cl)C#N)Cc1c(cccc1)Cl)C)C
|
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| Target and Pathway | |||||
| Target(s) | Progesterone receptor | Target Info | Agonist | [1] | |
| KEGG Pathway | Oocyte meiosis | ||||
| Progesterone-mediated oocyte maturation | |||||
| Pathway Interaction Database | Cellular roles of Anthrax toxin | ||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Nuclear Receptor transcription pathway | |||||
| WikiPathways | Ovarian Infertility Genes | ||||
| Signaling by ERBB4 | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 627). | ||||
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