Drug Information

Drug General Information
Drug ID
D02WST
Former ID
DIB009429
Drug Name
Unfractionated heparin
Synonyms
Elaprin; UFH (solid oral), Emisphere; Unfractionated heparin (solid oral, eligen); SNAC/heparin capsule (solid oral), Emisphere; SNAD/heparin tablet (solid oral), Emisphere; Unfractionated heparin (solid oral, eligen), Emisphere
Indication Thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] Phase 3 [526268]
Thrombosis [ICD9: 437.6, 453, 671.5, 671.9; ICD10:I80-I82] Phase 1 [549902]
Company
Emisphere Technologies Inc
Target and Pathway
Target(s) Antithrombin-III Target Info Modulator [533572]
KEGG Pathway Complement and coagulation cascades
PANTHER Pathway Blood coagulation
Pathway Interaction Database Glypican 1 network
Reactome Intrinsic Pathway of Fibrin Clot Formation
Common Pathway of Fibrin Clot Formation
WikiPathways Complement and Coagulation Cascades
Formation of Fibrin Clot (Clotting Cascade)
References
Ref 526268Bivalirudin as a replacement for unfractionated heparin in unstable angina/non-ST-elevation myocardial infarction: observations from the TIMI 8 trial. The Thrombolysis in Myocardial Infarction. Am Heart J. 2002 Feb;143(2):229-34.
Ref 549902Clinical pipeline report, company report or official report of Emisphere Technologies.
Ref 533572Heparin with low affinity to antithrombin III inhibits the activation of prothrombin in normal plasma. Thromb Res. 1982 Nov 15;28(4):487-97.

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