Drug General Information
Drug ID	D02XMQ
Former ID	DNC010366
Drug Name	1-amino-4-methoxyanthracene-9,10-dione
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[530650]
Structure		Download 2D MOL 3D MOL
Formula	C15H11NO3
Canonical SMILES	COC1=C2C(=C(C=C1)N)C(=O)C3=CC=CC=C3C2=O
InChI	1S/C15H11NO3/c1-19-11-7-6-10(16)12-13(11)15(18)9-5-3-2-4-8(9)14(12)17/h2-7H,16H2,1H3
InChIKey	KXOGXZAXERYOTC-UHFFFAOYSA-N
PubChem Compound ID	8321
Target and Pathway
Target(s)	Adenosine A2a receptor	Target Info	Inhibitor	[530650]
KEGG Pathway	Rap1 signaling pathway
	Calcium signaling pathway
	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Vascular smooth muscle contraction
	Parkinson's disease
	Alcoholism
Pathway Interaction Database	HIF-2-alpha transcription factor network
PathWhiz Pathway	Intracellular Signalling Through Adenosine Receptor A2a and Adenosine
Reactome	NGF-independant TRKA activation
	Adenosine P1 receptors
	G alpha (s) signalling events
	Surfactant metabolism
WikiPathways	Nucleotide GPCRs
	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	NGF signalling via TRKA from the plasma membrane
	GPCR ligand binding
	GPCR downstream signaling
	GPCRs, Other
References
Ref 530650	J Med Chem. 2010 Feb 25;53(4):1799-809.Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists.
Ref 530650	J Med Chem. 2010 Feb 25;53(4):1799-809.Structure-based discovery of novel chemotypes for adenosine A(2A) receptor antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.