Drug Information

Drug General Information
Drug ID
D02XXK
Former ID
DNC012470
Drug Name
(9-Benzyl-9H-purin-6-yl)-cyclopropyl-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [533033]
Structure
Download
2D MOL

3D MOL
Formula
C15H15N5
Canonical SMILES
C1CC1NC2=NC=NC3=C2N=CN3CC4=CC=CC=C4
InChI
1S/C15H15N5/c1-2-4-11(5-3-1)8-20-10-18-13-14(19-12-6-7-12)16-9-17-15(13)20/h1-5,9-10,12H,6-8H2,(H,16,17,19)
InChIKey
AVSPKBDDPGPKRA-UHFFFAOYSA-N
PubChem Compound ID
14022446
Target and Pathway
Target(s) Gamma-aminobutyric acid receptor subunit alpha-1 Target Info Inhibitor [533033]
Gamma-aminobutyric acid receptor Target Info Inhibitor [533033]
Gamma-aminobutyric acid receptor subunit gamma-2 Target Info Inhibitor [533033]
Gamma-aminobutyric acid receptor subunit beta-2 Target Info Inhibitor [533033]
KEGG Pathway Neuroactive ligand-receptor interaction
Retrograde endocannabinoid signaling
GABAergic synapse
Morphine addiction
Nicotine addictionhsa04080:Neuroactive ligand-receptor interaction
Serotonergic synapse
Nicotine addiction
Reactome Ligand-gated ion channel transport
GABA A receptor activationR-HSA-975298:Ligand-gated ion channel transport
GABA A receptor activation
WikiPathways SIDS Susceptibility Pathways
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transportWP2754:Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
Iron uptake and transport
References
Ref 533033J Med Chem. 1989 May;32(5):1020-4.Benzodiazepine receptor binding activity of 6,9-disubstituted purines.
Ref 533033J Med Chem. 1989 May;32(5):1020-4.Benzodiazepine receptor binding activity of 6,9-disubstituted purines.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.