Drug General Information
Drug ID	D02ZQM
Former ID	DNC009634
Drug Name	6-Pyridin-3-yl-1,2,3,4-tetrahydronaphthalen-2-ol
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529834]
Structure		Download 2D MOL 3D MOL
Formula	C15H15NO
Canonical SMILES	C1CC2=C(CC1O)C=CC(=C2)C3=CN=CC=C3
InChI	1S/C15H15NO/c17-15-6-5-11-8-12(3-4-13(11)9-15)14-2-1-7-16-10-14/h1-4,7-8,10,15,17H,5-6,9H2
InChIKey	ROYVUWJYYRTBSK-UHFFFAOYSA-N
PubChem Compound ID	25180104
Target and Pathway
Target(s)	Cytochrome P450 11B1, mitochondrial	Target Info	Inhibitor	[529834]
BioCyc Pathway	Superpathway of steroid hormone biosynthesis
	Glucocorticoid biosynthesis
	Mineralocorticoid biosynthesis
KEGG Pathway	Steroid hormone biosynthesis
	Metabolic pathways
PathWhiz Pathway	Steroidogenesis
Reactome	Glucocorticoid biosynthesis
	Endogenous sterols
WikiPathways	Metapathway biotransformation
	Oxidation by Cytochrome P450
	Metabolism of steroid hormones and vitamin D
	Corticotropin-releasing hormone
References
Ref 529834	J Med Chem. 2008 Dec 25;51(24):8077-87.In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives.
Ref 529834	J Med Chem. 2008 Dec 25;51(24):8077-87.In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives.

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