Drug Information

Drug General Information
Drug ID
D03AJS
Former ID
DNC008787
Drug Name
SERGLIFLOZIN A
Drug Type
Small molecular drug
Indication Discovery agent Investigative [530750]
Structure
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2D MOL

3D MOL
Formula
C20H24O7
Canonical SMILES
COC1=CC=C(C=C1)CC2=CC=CC=C2OC3C(C(C(C(O3)CO)O)O)O
InChI
1S/C20H24O7/c1-25-14-8-6-12(7-9-14)10-13-4-2-3-5-15(13)26-20-19(24)18(23)17(22)16(11-21)27-20/h2-9,16-24H,10-11H2,1H3/t16-,17-,18+,19-,20-/m1/s1
InChIKey
HFLCZNNDZKKXCS-OUUBHVDSSA-N
PubChem Compound ID
10177526
Target and Pathway
Target(s) mRNA of sodium-glucosetransporter-2 Target Info Inhibitor [530750]
Reactome Hexose transport
Na+-dependent glucose transporters
Inositol transporters
WikiPathways NRF2 pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
References
Ref 530750Bioorg Med Chem. 2010 Mar 15;18(6):2178-94. Epub 2010 Feb 4.Novel C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents: 1,3,4-Thiadiazolylmethylphenyl glucoside congeners.
Ref 530750Bioorg Med Chem. 2010 Mar 15;18(6):2178-94. Epub 2010 Feb 4.Novel C-aryl glucoside SGLT2 inhibitors as potential antidiabetic agents: 1,3,4-Thiadiazolylmethylphenyl glucoside congeners.

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