Drug Information

Drug General Information
Drug ID
D03ALC
Former ID
DNC001075
Drug Name
Oxindole 16 (compound 3)
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535564]
Structure
Download
2D MOL

3D MOL
Formula
C14H19F6N7O8
Canonical SMILES
C1CN2C(=NC(C3C2(C1(O)O)N=C(N3)N)COC(=O)N)N.C(=O)(C(F)(F<br />)F)O.C(=O)(C(F)(F)F)O
InChI
1S/C10H17N7O4.2C2HF3O2/c11-6-15-5-4(3-21-8(13)18)14-7(12)17-2-1-9(19,20)10(5,17)16-6;2*3-2(4,5)1(6)7/h4-5,19-20H,1-3H2,(H2,12,14)(H2,13,18)(H3,11,15,16);2*(H,6,7)/t4-,5-,10-;;/m0../s1
InChIKey
YOPZUWVTAZLOMO-UIPPETONSA-N
CAS Number
CAS 11017-04-2
PubChem Compound ID
11692221
PubChem Substance ID
16796551, 42859139, 79213135, 134340323
Target and Pathway
Target(s) Cell division protein kinase 8 Target Info Inhibitor [535564]
Cell division protein kinase 5 Target Info Inhibitor [535564]
KEGG Pathway Axon guidance
Alzheimer's disease
Cocaine addiction
NetPath Pathway EGFR1 Signaling Pathway
TCR Signaling Pathway
PANTHER Pathway Axon guidance mediated by semaphorins
Pathway Interaction Database Reelin signaling pathway
Glucocorticoid receptor regulatory network
Lissencephaly gene (LIS1) in neuronal migration and development
EPHA forward signaling
Trk receptor signaling mediated by the MAPK pathway
Reactome PPARA activates gene expression
NOTCH1 Intracellular Domain Regulates Transcription
SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
Transcriptional regulation of white adipocyte differentiationR-HSA-180024:DARPP-32 events
CRMPs in Sema3A signaling
Factors involved in megakaryocyte development and platelet production
WikiPathways Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Transcriptional Regulation of White Adipocyte Differentiation
Signaling by NOTCH1
SREBP signalling
Generic Transcription PathwayWP707:DNA Damage Response
BDNF signaling pathway
Alzheimers Disease
Opioid Signalling
Semaphorin interactions
Factors involved in megakaryocyte development and platelet production
Nicotine Activity on Dopaminergic Neurons
miRNA Regulation of DNA Damage Response
References
Ref 535564Pharmacological inhibitors of cyclin-dependent kinases. Trends Pharmacol Sci. 2002 Sep;23(9):417-25.
Ref 535564Pharmacological inhibitors of cyclin-dependent kinases. Trends Pharmacol Sci. 2002 Sep;23(9):417-25.

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