Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03AZU
|
||||
| Former ID |
DIB016114
|
||||
| Drug Name |
Org-31710
|
||||
| Synonyms |
Org-31806
|
||||
| Drug Type |
Small molecular drug
|
||||
| Indication | Contraception [ICD10:Z30] | Discontinued in Phase 1 | [1] | ||
| Company |
Organon BioSciences
|
||||
| Structure |
|
Download2D MOL |
|||
| Formula |
C30H39NO2
|
||||
| Canonical SMILES |
C12=C3C(=CC(=O)CC3)[C@@H](C[C@H]1[C@H]1[C@](C[C@@H]2c2c<br />cc(N(C)C)cc2)([C@@]2(OCCC2)CC1)C)C
|
||||
| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Progesterone receptor | Target Info | Modulator | [2] | |
| KEGG Pathway | Oocyte meiosis | ||||
| Progesterone-mediated oocyte maturation | |||||
| Pathway Interaction Database | Cellular roles of Anthrax toxin | ||||
| Reactome | Nuclear signaling by ERBB4 | ||||
| Nuclear Receptor transcription pathway | |||||
| WikiPathways | Ovarian Infertility Genes | ||||
| Signaling by ERBB4 | |||||
| Nuclear Receptors | |||||
| References | |||||
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002550) | ||||
| REF 2 | Progesterone receptor antagonists Org 31710 and RU 486 increase apoptosis in human periovulatory granulosa cells. Fertil Steril. 2001 Dec;76(6):1225-31. | ||||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.