TTD | Drug: D03BIQ

Drug General Information
Drug ID	D03BIQ
Former ID	DNC006947
Drug Name	ADS-102891
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528581]
Structure		Download 2D MOL 3D MOL
Formula	C22H21F3N4O2
Canonical SMILES	CC1=NC(=NC2=C1C=C(C=C2)NC(=O)COC3=CC=C(C=C3)C(F)(F)F)N4<br />CCCC4
InChI	1S/C22H21F3N4O2/c1-14-18-12-16(6-9-19(18)28-21(26-14)29-10-2-3-11-29)27-20(30)13-31-17-7-4-15(5-8-17)22(23,24)25/h4-9,12H,2-3,10-11,13H2,1H3,(H,27,30)
InChIKey	UPUPELYLRJEQHO-UHFFFAOYSA-N
PubChem Compound ID	11189610
Target and Pathway
Target(s)	Melanin-concentrating hormone receptor 1	Target Info	Inhibitor	[528581]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 528581	Bioorg Med Chem Lett. 2007 Mar 1;17(5):1403-7. Epub 2006 Dec 2.Quinazoline and benzimidazole MCH-1R antagonists.
Ref 528581	Bioorg Med Chem Lett. 2007 Mar 1;17(5):1403-7. Epub 2006 Dec 2.Quinazoline and benzimidazole MCH-1R antagonists.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information