Drug Information

Drug General Information
Drug ID
D03CDK
Former ID
DIB006971
Drug Name
ASP-7147
Indication Irritable bowel syndrome [ICD9: 564.1, 787.91; ICD10:A09, K58, K59.1] Phase 2 [524356]
Company
Astellas Pharma Inc
Target and Pathway
Target(s) Gastrin-releasing peptide receptor Target Info Antagonist [550285]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Peptide GPCRs
GPCRs, Other
References
Ref 524356ClinicalTrials.gov (NCT01896583) A Phase 2 Pilot Study to Assess ASP7147 in Patients With Diarrhea Predominant Irritable Bowel Syndrome (IBS-D). U.S. National Institutes of Health.
Ref 550285Astellas and Drais Partner To Develop Third Astellas Compound through Tacurion

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