Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03CMR
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| Former ID |
DIB000600
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| Drug Name |
TER-16998
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| Synonyms |
TER-16998; TER-17411; TER-17529; TLK-16998; TLK-17411; TLK-19780; TLK-19781; Insulin receptor activators (oral, diabetes mellitus); Insulin receptor activators (oral, diabetes mellitus), ReceptorBio; Insulin receptor activators (oral, diabetes), Telik/Sanwa
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| Indication | Diabetes [ICD9: 253.5, 588.1; ICD10:E23.2, N25.1] | Terminated | [546270] | ||
| Company |
Telik Inc
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| Structure |
|
Download2D MOL |
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| Canonical SMILES |
S(=O)(=O)(c1cc(c2c(c1)cc(NC(=O)Nc1cc3c(c(cc(S(=O)(=O)Nc<br />4cc(S(=O)(=O)O)c(cc4)Cl)c3)O)cc1)cc2)O)Nc1cc(S(=O)(=O)O<br />)c(cc1)Cl
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| CAS Number |
CAS 210978-64-6
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| Target and Pathway | |||||
| Target(s) | Insulin receptor | Target Info | Activator | [543489] | |
| KEGG Pathway | Ras signaling pathway | ||||
| Rap1 signaling pathway | |||||
| cGMP-PKG signaling pathway | |||||
| HIF-1 signaling pathway | |||||
| FoxO signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| AMPK signaling pathway | |||||
| Adherens junction | |||||
| Insulin signaling pathway | |||||
| Ovarian steroidogenesis | |||||
| Type II diabetes mellitus | |||||
| Non-alcoholic fatty liver disease (NAFLD) | |||||
| Aldosterone-regulated sodium reabsorption | |||||
| NetPath Pathway | TGF_beta_Receptor Signaling Pathway | ||||
| Pathway Interaction Database | Insulin Pathway | ||||
| Signaling events mediated by PTP1B | |||||
| Signaling events mediated by TCPTP | |||||
| Insulin-mediated glucose transport | |||||
| PathWhiz Pathway | Insulin Signalling | ||||
| Leucine Stimulation on Insulin Signaling | |||||
| References | |||||
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