Drug Information

Drug General Information
Drug ID
D03DKR
Former ID
DIB012428
Drug Name
GALAMUSTINE HYDROCHLORIDE
Synonyms
C6-GLM; C6-GalM; C6-Galactose mustard; G-6-M; Galamustine hydrochloride < Rec INNM >; 6-[Bis(2-chloroethyl)amino]-6-deoxy-D-galactopyranose hydrochloride
Drug Type
Small molecular drug
Indication Solid tumours [ICD9: 140-199, 210-229; ICD10:C00-D48] Phase 1 [545215]
Structure
Download
2D MOL

3D MOL
Formula
C10H19Cl2NO5
Canonical SMILES
C(CCl)N(CCCl)CC1C(C(C(C(O1)O)O)O)O
InChI
1S/C10H19Cl2NO5/c11-1-3-13(4-2-12)5-6-7(14)8(15)9(16)10(17)18-6/h6-10,14-17H,1-5H2/t6-,7+,8+,9-,10?/m1/s1
InChIKey
COKGUJJIBXWRNV-CYNREMDZSA-N
CAS Number
CAS 105618-02-8
PubChem Compound ID
65891
PubChem Substance ID
8190015, 15395204, 43122630, 57315809, 79682698, 104334943, 117472572, 126683027, 127654619, 135024017, 160703441, 179149532, 223653808, 228250265
Target and Pathway
Target(s) Human DNA Target Info Antagonist [533485]
References
Ref 545215Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002476)
Ref 5334856-[Bis(2-chloroethyl)amino]-6-deoxygalactopyranose hydrochloride (C6-galactose mustard), a new alkylating agent with reduced bone marrow toxicity. Cancer Res. 1987 Feb 1;47(3):696-9.

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