TTD | Drug: D03ECU

Drug General Information
Drug ID	D03ECU
Former ID	DIB018158
Drug Name	[125I]iodophenpropit
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540582]
Structure		Download 2D MOL 3D MOL
Formula	C15H21IN4S
InChI	InChI=1S/C15H21IN4S/c16-13-5-3-12(4-6-13)7-8-19-15(17)21-9-1-2-14-10-18-11-20-14/h3-6,10-11,15,19H,1-2,7-9,17H2,(H,18,20)/t15-/m0/s1
InChIKey	UWFACTDPNOOPFV-HNNXBMFYSA-N
PubChem Compound ID	5311186
Target and Pathway
Target(s)	Histamine H3 receptor	Target Info	Antagonist	[533760]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Histamine receptors
Reactome	G alpha (i) signalling events
WikiPathways	Monoamine Transport
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 540582	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3960).
Ref 533760	Characterization of the binding of the first selective radiolabelled histamine H3-receptor antagonist, [125I]-iodophenpropit, to rat brain. Br J Pharmacol. 1994 Oct;113(2):355-62.

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Drug Information