| Drug General Information |
| Drug ID |
D03FPU
|
| Former ID |
DAP001496
|
| Drug Name |
Methamfetamine
|
| Drug Type |
Small molecular drug
|
| Indication |
Pain; Inflammatory diseases [ICD9: 338,780; ICD10:R52, G89]
|
Approved |
[1]
|
|---|
| Therapeutic Class |
Analgesics
|
| Structure |
|
Download
2D MOL
3D MOL
|
| Formula |
C10H15N
|
| Canonical SMILES |
CC(CC1=CC=CC=C1)NC
|
| InChI |
1S/C10H15N/c1-9(11-2)8-10-6-4-3-5-7-10/h3-7,9,11H,8H2,1-2H3/t9-/m0/s1
|
| InChIKey |
MYWUZJCMWCOHBA-VIFPVBQESA-N
|
| CAS Number |
CAS 537-46-2
|
| PubChem Compound ID |
|
| PubChem Substance ID |
9373, 86393, 841176, 7979916, 8157860, 10318874, 15194699, 29229287, 46508541, 47217054, 47365454, 47515585, 47960002, 50004327, 53789276, 56311093, 56312330, 56313865, 56314133, 56314533, 57288565, 57326508, 76939162, 85239987, 96024877, 104234344, 104324404, 117516537, 128667762, 134337864, 134338686, 134977993, 136963523, 137001219, 142148255, 160964817, 164187274, 175268005, 175269473, 175443906, 178101505, 179252637, 184547219, 223856686, 226427302, 241092821, 250138934, 250231443
|
| ChEBI ID |
ChEBI:6809
|
| SuperDrug ATC ID |
N06BA03
|
| SuperDrug CAS ID |
cas=000537462
|
| Target and Pathway |
| Target(s) |
D(2) dopamine receptor |
Target Info |
Agonist |
[1]
|
|---|
|
KEGG Pathway
|
Rap1 signaling pathway
|
|
cAMP signaling pathway
|
|
Neuroactive ligand-receptor interaction
|
|
Gap junction
|
|
Dopaminergic synapse
|
|
Parkinson's disease
|
|
Cocaine addiction
|
|
Alcoholism
|
|
PANTHER Pathway
|
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
|
|
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
|
|
Dopamine receptor mediated signaling pathway
|
|
Nicotine pharmacodynamics pathway
|
|
Reactome
|
Dopamine receptors
|
|
G alpha (i) signalling events
|
|
WikiPathways
|
Hypothetical Network for Drug Addiction
|
|
Monoamine GPCRs
|
|
GPCRs, Class A Rhodopsin-like
|
|
Genes and (Common) Pathways Underlying Drug Addiction
|
|
GPCR ligand binding
|
|
GPCR downstream signaling
|
|
Nicotine Activity on Dopaminergic Neurons
|
| References |
| REF 1 | Pharmacotherapy for obesity. Drugs. 2005;65(10):1391-418. |
|---|
