Drug General Information
Drug ID	D03GAQ
Former ID	DNC004188
Drug Name	8-Methyl-1,3-dihydro-imidazo[4,5-b]quinolin-2-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[528087]
Structure		Download 2D MOL 3D MOL
Formula	C11H9N3O
Canonical SMILES	CC1=C2C=C3C(=NC2=CC=C1)NC(=O)N3
InChI	1S/C11H9N3O/c1-6-3-2-4-8-7(6)5-9-10(12-8)14-11(15)13-9/h2-5H,1H3,(H2,12,13,14,15)
InChIKey	NFWDGDAZJTYAHA-UHFFFAOYSA-N
PubChem Compound ID	15065156
Target and Pathway
Target(s)	CGMP-inhibited 3',5'-cyclic phosphodiesterase A	Target Info	Inhibitor	[528087]
KEGG Pathway	Purine metabolism
	cGMP-PKG signaling pathway
	cAMP signaling pathway
	Morphine addiction
Reactome	cGMP effects
	G alpha (s) signalling events
WikiPathways	miR-targeted genes in muscle cell - TarBase
	miR-targeted genes in lymphocytes - TarBase
References
Ref 528087	J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.
Ref 528087	J Med Chem. 1991 Sep;34(9):2906-16.1,3-Dihydro-2H-imidazo[4,5-b]quinolin-2-ones--inhibitors of blood platelet cAMP phosphodiesterase and induced aggregation.

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