Drug General Information
Drug ID	D03GLM
Former ID	DIB015633
Drug Name	BMS-210285
Drug Type	Small molecular drug
Indication	Type 2 diabetes [ICD9: 250; ICD10:E11]		Terminated	[546852]
Company	Bristol-Myers Squibb Co
Structure		Download 2D MOL 3D MOL
Formula	C24H25ClF2N2O5S
Canonical SMILES	S(=O)(=O)(Nc1cc(ccc1O)[C@H](CN[C@@H](c1ccc(OC(F)F)cc1)C<br />c1cc(Cl)ccc1)O)C
CAS Number	CAS 344607-69-8
PubChem Compound ID	9828292
Target and Pathway
Target(s)	Beta-3 adrenergic receptor	Target Info	Agonist	[551898]
KEGG Pathway	Calcium signaling pathway
	cGMP-PKG signaling pathway
	Neuroactive ligand-receptor interaction
	Endocytosis
	Salivary secretion
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Beta3 adrenergic receptor signaling pathway
Reactome	Adrenoceptors
	G alpha (s) signalling events
WikiPathways	Monoamine GPCRs
	Calcium Regulation in the Cardiac Cell
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 546852	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800010623)
Ref 551898	CA patent application no. 509835, Nitrogen-containing heterocyclic derivatives, medicinal compositions containing the same and medicinal use thereof.

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