Drug General Information
Drug ID	D03INQ
Former ID	DIB004185
Drug Name	Laevo-Bambuterol
Synonyms	R-Bambuterol; R-bambuterol hydrochloride
Indication	Asthma [ICD10:J45]		Phase 1	[549077]
Company	Dongguan Kaifa Biomedicine Inc
Structure		Download 2D MOL 3D MOL
Canonical SMILES	CC(C)(NC[C@@H](c1cc(OC(=O)N(C)C)cc(OC(=O)N(C)C)c1)O)C.C<br />l
Target and Pathway
Target(s)	Beta-3 adrenergic receptor	Target Info	Modulator	[543746]
KEGG Pathway	Calcium signaling pathway
	cGMP-PKG signaling pathway
	Neuroactive ligand-receptor interaction
	Endocytosis
	Salivary secretion
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Beta3 adrenergic receptor signaling pathway
Reactome	Adrenoceptors
	G alpha (s) signalling events
WikiPathways	Monoamine GPCRs
	Calcium Regulation in the Cardiac Cell
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 549077	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031995)
Ref 543746	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 29).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.