Drug Information

Drug General Information
Drug ID
D03JQD
Former ID
DIB018967
Drug Name
BETP
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542575]
Structure
Download
2D MOL
Formula
C20H17F3N2O2S
InChI
InChI=1S/C20H17F3N2O2S/c1-2-28(26)19-24-17(12-18(25-19)20(21,22)23)15-9-6-10-16(11-15)27-13-14-7-4-3-5-8-14/h3-12H,2,13H2,1H3
InChIKey
NTDFYGSSDDMNHI-UHFFFAOYSA-N
PubChem Compound ID
49868481
PubChem Substance ID
104503558, 163685708, 183814150, 196373095, 223365920, 241377174, 249691293, 249810663, 252158348, 252160868
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Modulator (allosteric modulator) [532871]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 542575(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7585).
Ref 532871A potentiator of orthosteric ligand activity at GLP-1R acts via covalent modification. Nat Chem Biol. 2014 Aug;10(8):629-31.

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