Drug General Information
Drug ID	D03LFR
Former ID	DCL000392
Drug Name	SB-756050
Indication	Type 2 diabetes [ICD9: 250; ICD10:E11]		Discontinued in Phase 2	[548743]
Company	GlaxoSmithKline
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Bile acid receptor	Target Info	Agonist	[550963]
KEGG Pathway	Bile secretion
Pathway Interaction Database	RXR and RAR heterodimerization with other nuclear receptor
Reactome	Recycling of bile acids and salts
	PPARA activates gene expression
	Endogenous sterols
WikiPathways	Nuclear Receptors in Lipid Metabolism and Toxicity
	Nuclear Receptors Meta-Pathway
	Farnesoid X Receptor Pathway
	Drug Induction of Bile Acid Pathway
References
Ref 548743	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028284)
Ref 550963	Clinical pipeline report, company report or official report of GlaxoSmithKline (2009).

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