Drug Information

Drug General Information
Drug ID
D03LIP
Former ID
DIB019987
Drug Name
GW841819X
Synonyms
KB-75882
Drug Type
Small molecular drug
Indication Discovery agent Investigative [542528]
Structure
Download
2D MOL
Formula
C25H21N5O2
InChI
InChI=1S/C25H21N5O2/c1-17-28-29-24-23(27-25(31)32-16-18-10-4-2-5-11-18)26-22(19-12-6-3-7-13-19)20-14-8-9-15-21(20)30(17)24/h2-15,23H,16H2,1H3,(H,27,31)
InChIKey
TUWDLUFFAHHNEF-UHFFFAOYSA-N
PubChem Compound ID
13953710
PubChem Substance ID
123047641, 129317347, 163323629, 172918749, 187051816, 224610933, 234870311
Target and Pathway
Target(s) Bromodomain-containing protein 3 Target Info Inhibitor [531473]
Bromodomain-containing protein 4 Target Info Inhibitor [531473]
Bromodomain-containing protein 2 Target Info Inhibitor [531473]
NetPath Pathway IL2 Signaling PathwayNetPath_7:TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database Regulation of retinoblastoma protein
WikiPathways Chemical Compounds to monitor ProteinsWP3295:Chemical Compounds to monitor ProteinsWP3295:Chemical Compounds to monitor Proteins
References
Ref 542528(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7514).
Ref 531473Discovery and characterization of small molecule inhibitors of the BET family bromodomains. J Med Chem. 2011 Jun 9;54(11):3827-38.

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