Drug Information

Drug General Information
Drug ID
D03MSV
Former ID
DNCL002906
Drug Name
PB-1023
Indication Type 2 diabetes [ICD9: 250; ICD10:E11] Phase 2 [550056]
Company
PhaseBio Pharmaceuticals
Target and Pathway
Target(s) Glucagon-like peptide 1 receptor Target Info Modulator [550091]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Reactome Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
G alpha (s) signalling events
Glucagon-type ligand receptors
WikiPathways GPCRs, Class B Secretin-like
Integration of energy metabolism
GPCR ligand binding
GPCR downstream signaling
References
Ref 550056Clinical pipeline report, company report or official report of PhaseBio Pharmaceuticals.
Ref 550091On-target Effects of GLP-1 Receptor Agonists on Thyroid C-cells in Rats and Mice. Toxicol Pathol February 2013 vol. 41 no. 2 303-309.

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