Drug General Information
Drug ID	D03MYO
Former ID	DIB001166
Drug Name	MGL-3196
Indication	Hyperlipidaemia [ICD9: 272.0-272.4; ICD10:E78]		Phase 1	[532494]
Company	Madrigal pharmaceuticals
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Thyroid hormone receptor beta-1	Target Info	Agonist	[532494]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Thyroid hormone signaling pathway
Pathway Interaction Database	RXR and RAR heterodimerization with other nuclear receptor
Reactome	Nuclear Receptor transcription pathway
WikiPathways	SIDS Susceptibility Pathways
	Hematopoietic Stem Cell Differentiation
	Nuclear Receptors
References
Ref 532494	Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-beta agonist. Atherosclerosis. 2013 Oct;230(2):373-80.
Ref 532494	Lipid lowering in healthy volunteers treated with multiple doses of MGL-3196, a liver-targeted thyroid hormone receptor-beta agonist. Atherosclerosis. 2013 Oct;230(2):373-80.

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