TTD | Drug: D03NOS

Drug General Information
Drug ID	D03NOS
Former ID	DIB004010
Drug Name	Rimiterol
Drug Type	Small molecular drug
Indication	Asthma [ICD10:J45]		Approved	[551871]
Structure		Download 2D MOL 3D MOL
Formula	C12H18BrNO3
Canonical SMILES	O[C@@H]([C@@H]1CCCCN1)c2ccc(O)c(O)c2
InChI	1S/C12H17NO3/c14-10-5-4-8(7-11(10)15)12(16)9-3-1-2-6-13-9/h4-5,7,9,12-16H,1-3,6H2/t9-,12+/m0/s1
InChIKey	IYMMESGOJVNCKV-JOYOIKCWSA-N
PubChem Compound ID	70685132
Target and Pathway
Target(s)	Beta-3 adrenergic receptor	Target Info	Modulator	[525848], [551871]
KEGG Pathway	Calcium signaling pathway
	cGMP-PKG signaling pathway
	Neuroactive ligand-receptor interaction
	Endocytosis
	Salivary secretion
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
PANTHER Pathway	Beta3 adrenergic receptor signaling pathway
Reactome	Adrenoceptors
Reactome	G alpha (s) signalling events
WikiPathways	Monoamine GPCRs
	Calcium Regulation in the Cardiac Cell
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 525848	Comparison of the beta2-adrenoceptor selectivity of rimiterol, salbutamol and isoprenaline by the intravenous route in man. Br J Clin Pharmacol. 1975 Feb;2(1):41-8.
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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Drug Information