TTD | Drug: D03OCG

Drug General Information
Drug ID	D03OCG
Former ID	DIB011667
Drug Name	FGF-21
Synonyms	Fibroblast growth factor 21, Lilly; LP-10152; FGF-21, Lilly
Indication	Type 2 diabetes [ICD9: 250; ICD10:E11]		Discontinued in Phase 1/2	[548772]
Company	Eli Lilly & Co
Target and Pathway
Target(s)	FGF-21 ligand	Target Info	Agonist	[548773]
KEGG Pathway	MAPK signaling pathway
	Ras signaling pathway
	Rap1 signaling pathway
	PI3K-Akt signaling pathway
	Regulation of actin cytoskeleton
	Pathways in cancer
	Melanoma
Reactome	Facilitative Na+-independent glucose transporters
Reactome	Glucose transport
WikiPathways	Regulation of Actin Cytoskeleton
	Aryl Hydrocarbon Receptor
	SREBP signalling
References
Ref 548772	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028644)
Ref 548773	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028644)

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Drug Information