TTD | Drug: D03OCS

Drug General Information
Drug ID	D03OCS
Former ID	DIB020317
Drug Name	ME36
Synonyms	N-ethyl,N-methyl EM-A
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[538923]
Structure		Download 2D MOL
Formula	C38H69NO13
InChI	InChI=1S/C38H69NO13/c1-14-26-38(11,46)31(42)21(5)28(40)19(3)17-36(9,45)33(52-35-29(41)25(39(12)15-2)16-20(4)48-35)22(6)30(23(7)34(44)50-26)51-27-18-37(10,47-13)32(43)24(8)49-27/h19-27,29-33,35,41-43,45-46H,14-18H2,1-13H3
InChIKey	DYYAPFZVDGCKCL-UHFFFAOYSA-N
PubChem Compound ID	14487390
PubChem Substance ID	135652703
Target and Pathway
Target(s)	Motilin receptor	Target Info	Agonist	[527468]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 538923	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1447).
Ref 527468	Desensitization of the human motilin receptor by motilides. J Pharmacol Exp Ther. 2005 Jun;313(3):1397-405. Epub 2005 Mar 11.

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Drug Information