Drug Information

Drug General Information
Drug ID
D03PVV
Former ID
DIB018513
Drug Name
1-palmitoyl-lysophosphatidylcholine
Synonyms
lysophosphatidylcholine(16:0); LPC 16:0
Drug Type
Small molecular drug
Indication Discovery agent Investigative [540996]
Structure
Download
2D MOL
Formula
C24H50NO7P
InChI
InChI=1S/C24H50NO7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-24(27)30-21-23(26)22-32-33(28,29)31-20-19-25(2,3)4/h23,26H,5-22H2,1-4H3/t23-/m0/s1
InChIKey
ASWBNKHCZGQVJV-QHCPKHFHSA-N
PubChem Compound ID
10097314
PubChem Substance ID
15084709, 22506700, 39157190, 57374179, 78590941, 135371341, 137324605, 138820931, 152051207, 178102278, 179660958
Target and Pathway
Target(s) Glucose-dependent insulinotropic receptor Target Info Agonist [527346]
KEGG Pathway cAMP signaling pathway
Insulin secretion
WikiPathways Incretin Synthesis, Secretion, and Inactivation
References
Ref 540996(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5650).
Ref 527346Lysophosphatidylcholine enhances glucose-dependent insulin secretion via an orphan G-protein-coupled receptor. Biochem Biophys Res Commun. 2005 Jan 28;326(4):744-51.

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