Drug Information

Drug General Information
Drug ID
D03PVY
Former ID
DIB014183
Drug Name
GlycoPEGylated erythropoietin
Synonyms
GlycoPEGylated EPO, Neose; GlycoPEGylated erythropoietin, Neose; GlycoPeg-EPO; NE-180
Indication Cancer [ICD9: 140-229; ICD10:C00-C96] Discontinued in Phase 2 [547682]
Company
Neose Technologies
Target and Pathway
Target(s) Erythropoietin Receptor Target Info Modulator [544013]
KEGG Pathway Cytokine-cytokine receptor interaction
PI3K-Akt signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
NetPath Pathway TGF_beta_Receptor Signaling Pathway
Pathway Interaction Database Signaling events mediated by Stem cell factor receptor (c-Kit)
EPO signaling pathway
WikiPathways EPO Receptor Signaling
References
Ref 547682Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800018390)
Ref 544013Design of Homogeneous, MonoPEGylated Erythropoietin Analogs With Preserved In Vitro Bioactivity. Exp Hematol. 2006 June; 34(6): 697-704.

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