TTD | Drug: D03QZB

Drug General Information
Drug ID	D03QZB
Former ID	DIB012733
Drug Name	F-1394
Drug Type	Small molecular drug
Indication	Arteriosclerosis [ICD9: 440; ICD10:I70]		Discontinued in Phase 1	[545396]
Company	Fujirebio KK
Structure		Download 2D MOL 3D MOL
Formula	C33H61N3O6
Canonical SMILES	C(=O)(N[C@@H]1[C@@H](OC(=O)CCNC(=O)[C@@H]2OC(OCC2(C)C)(<br />C)C)CCCC1)N(CC(C)(C)C)CCCCCCCCC
CAS Number	CAS 162490-89-3
PubChem Compound ID	6918210
Target and Pathway
Target(s)	Liver carboxylesterase	Target Info	Modulator	[526020]
KEGG Pathway	Drug metabolism - other enzymes
KEGG Pathway	Metabolic pathways
Pathway Interaction Database	E2F transcription factor network
WikiPathways	NRF2 pathway
	Nuclear Receptors Meta-Pathway
	Heroin metabolism
	Irinotecan Pathway
	Fluoropyrimidine Activity
	Phase I biotransformations, non P450
References
Ref 545396	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003109)
Ref 526020	ACAT inhibitor F-1394 prevents intimal hyperplasia induced by balloon injury in rabbits. J Lipid Res. 2001 Apr;42(4):480-8.

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Drug Information