TTD | Drug: D03SXN

Drug General Information
Drug ID	D03SXN
Former ID	DNC003722
Drug Name	CP-96345
Drug Type	Small molecular drug
Indication	Discovery agent		Terminated	[544830]
Structure		Download 2D MOL 3D MOL
Formula	C28H32N2O
Canonical SMILES	COC1=CC=CC=C1CNC2C3CCN(C2C(C4=CC=CC=C4)C5=CC=CC=C5)CC3
InChI	1S/C28H32N2O/c1-31-25-15-9-8-14-24(25)20-29-27-23-16-18-30(19-17-23)28(27)26(21-10-4-2-5-11-21)22-12-6-3-7-13-22/h2-15,23,26-29H,16-20H2,1H3/t27-,28-/m0/s1
InChIKey	FLNYLINBEZROPL-NSOVKSMOSA-N
PubChem Compound ID	104943
Target and Pathway
Target(s)	Substance-P receptor	Target Info	Inhibitor	[551274]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Measles
PANTHER Pathway	CCKR signaling map ST
Reactome	G alpha (q) signalling events
WikiPathways	SIDS Susceptibility Pathways
	Gastrin-CREB signalling pathway via PKC and MAPK
	Spinal Cord Injury
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 544830	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001257)
Ref 551274	2-Aryl-1-azabicyclo[2.2.2]octanes as novel nonpeptide substance P antagonists, Bioorg. Med. Chem. Lett. 4(6):839-842 (1994).

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Drug Information