Drug Information

Drug General Information
Drug ID
D03TBA
Former ID
DIB020851
Drug Name
RPR121154
Synonyms
RPR-121154
Drug Type
Small molecular drug
Indication Discovery agent Investigative [541120]
Structure
Download
2D MOL
Formula
C22H23N3O
InChI
InChI=1S/C22H23N3O/c1-24-22(23)25-19-12-13-21(20(16-19)18-10-6-3-7-11-18)26-15-14-17-8-4-2-5-9-17/h2-13,16H,14-15H2,1H3,(H3,23,24,25)
InChIKey
QXDMVRPQHNFBSZ-UHFFFAOYSA-N
PubChem Compound ID
10020451
PubChem Substance ID
15001736, 44112543, 79375694, 103431675, 104133004, 178100220
Target and Pathway
Target(s) C5aR Target Info Antagonist [543765]
KEGG Pathway Neuroactive ligand-receptor interaction
Complement and coagulation cascades
Staphylococcus aureus infection
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathway
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways Complement and Coagulation Cascades
Human Complement System
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 541120(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 580).
Ref 543765(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 32).

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.