Drug Information

Drug General Information
Drug ID
D04ATN
Former ID
DNC012649
Drug Name
4-[3-(4-Ethynyl-phenoxy)-propyl]-1H-imidazole
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525896]
Structure
Download
2D MOL

3D MOL
Formula
C14H14N2O
Canonical SMILES
C#CC1=CC=C(C=C1)OCCCC2=CN=CN2
InChI
1S/C14H14N2O/c1-2-12-5-7-14(8-6-12)17-9-3-4-13-10-15-11-16-13/h1,5-8,10-11H,3-4,9H2,(H,15,16)
InChIKey
LMKPPWNWUJXSAQ-UHFFFAOYSA-N
PubChem Compound ID
10082417
Target and Pathway
Target(s) Histamine H3 receptor Target Info Inhibitor [525896]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 525896Bioorg Med Chem Lett. 2000 Oct 16;10(20):2379-82.Analogues and derivatives of ciproxifan, a novel prototype for generating potent histamine H3-receptor antagonists.
Ref 525896Bioorg Med Chem Lett. 2000 Oct 16;10(20):2379-82.Analogues and derivatives of ciproxifan, a novel prototype for generating potent histamine H3-receptor antagonists.

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