Drug Information

Drug General Information
Drug ID
D04BUH
Former ID
DCL000753
Drug Name
Cizolirtine
Synonyms
Cizolirtine [INN]; N,N-dimethyl-2-[(2-methylpyrazol-3-yl)-phenylmethoxy]ethanamine; N,N-dimethyl-2-[(R)-(2-methylpyrazol-3-yl)-phenylmethoxy]ethanamine
Drug Type
Small molecular drug
Indication Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0] Phase 2 [536374]
Therapeutic Class
Analgesics
Company
Esteve Laboratories
Structure
Download
2D MOL

3D MOL
Formula
C15H21N3O
Canonical SMILES
CN1C(=CC=N1)C(C2=CC=CC=C2)OCCN(C)C
InChI
1S/C15H21N3O/c1-17(2)11-12-19-15(13-7-5-4-6-8-13)14-9-10-16-18(14)3/h4-10,15H,11-12H2,1-3H3
InChIKey
DCMJBKFKXGPPMT-UHFFFAOYSA-N
CAS Number
CAS 142155-44-0
PubChem Compound ID
132412
PubChem Substance ID
11542386, 14798933, 29310562, 50540542, 103302567, 104377380, 127714817, 142327601, 179322217, 224073130, 226633388
Target and Pathway
Target(s) Calcitonin gene-related peptide 1 Target Info Inhibitor [536374]
Reactome G alpha (s) signalling events
Calcitonin-like ligand receptors
WikiPathways Myometrial Relaxation and Contraction Pathways
Endothelin Pathways
GPCR ligand binding
GPCR downstream signaling
References
Ref 536374Emerging drugs in neuropathic pain. Expert Opin Emerg Drugs. 2007 Mar;12(1):113-26.
Ref 536374Emerging drugs in neuropathic pain. Expert Opin Emerg Drugs. 2007 Mar;12(1):113-26.

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